BDBM179349 US9126952, 52

SMILES: Cc1nc(CC2CCCN(C2)c2ncnc3cc(ccc23)N2CCOCC2)sc1C

InChI Key: InChIKey=MQRVZBADYAFMHA-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179349   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM179349 (US9126952, 52) Show SMILES Cc1nc(CC2CCCN(C2)c2ncnc3cc(ccc23)N2CCOCC2)sc1C Show InChI InChI=1S/C23H29N5OS/c1-16-17(2)30-22(26-16)12-18-4-3-7-28(14-18)23-20-6-5-19(13-21(20)24-15-25-23)27-8-10-29-11-9-27/h5-6,13,15,18H,3-4,7-12,14H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.4	25
Merck Patent GmbH US Patent					Assay Description The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ...				US Patent US9126952 (2015) BindingDB Entry DOI: 10.7270/Q2JH3JZ2
					More data for this Ligand-Target Pair