BDBM179364 US9126952, 67

SMILES: Clc1nc(N2CCCC(C2)NS(=O)(=O)c2cccs2)c2ccc(cc2n1)N1CCOCC1

InChI Key: InChIKey=FGFIEWAMRZGKMB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179364   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM179364 (US9126952, 67) Show SMILES Clc1nc(N2CCCC(C2)NS(=O)(=O)c2cccs2)c2ccc(cc2n1)N1CCOCC1 Show InChI InChI=1S/C21H24ClN5O3S2/c22-21-23-18-13-16(26-8-10-30-11-9-26)5-6-17(18)20(24-21)27-7-1-3-15(14-27)25-32(28,29)19-4-2-12-31-19/h2,4-6,12-13,15,25H,1,3,7-11,14H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.4	25
Merck Patent GmbH US Patent					Assay Description The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ...				US Patent US9126952 (2015) BindingDB Entry DOI: 10.7270/Q2JH3JZ2
					More data for this Ligand-Target Pair