BDBM18294 (2R,4S,5S,7S)-5-amino-N-{2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]ethyl}-4-hydroxy-7-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-2,8-dimethylnonanamide::8-phenyl-octanecarboxamide peptidomimetic, 51

SMILES: COCCCOc1cc(C[C@@H](C[C@H](N)[C@@H](O)C[C@@H](C)C(=O)NCCN2C[C@H](C)O[C@H](C)C2)C(C)C)ccc1OC

InChI Key: InChIKey=FJPZRFMUNBBITF-VHSORMFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18294   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM18294 ((2R,4S,5S,7S)-5-amino-N-{2-[(2R,6S)-2,6-dimethylmo...) Show SMILES COCCCOc1cc(C[C@@H](C[C@H](N)[C@@H](O)C[C@@H](C)C(=O)NCCN2C[C@H](C)O[C@H](C)C2)C(C)C)ccc1OC |r| Show InChI InChI=1S/C31H55N3O6/c1-21(2)26(16-25-9-10-29(38-7)30(17-25)39-14-8-13-37-6)18-27(32)28(35)15-22(3)31(36)33-11-12-34-19-23(4)40-24(5)20-34/h9-10,17,21-24,26-28,35H,8,11-16,18-20,32H2,1-7H3,(H,33,36)/t22-,23-,24+,26+,27+,28+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals					Assay Description Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...				J Med Chem 50: 4818-31 (2007) Article DOI: 10.1021/jm070314y BindingDB Entry DOI: 10.7270/Q2MG7MSF
					More data for this Ligand-Target Pair