null

SMILES: CC(C)Oc1ccc(cc1Cl)\N=c1/[nH]c(=O)n(CCC(C)(C)C(=O)OCc2ccccc2)c(=O)n1Cc1ccc(Cl)cc1

InChI Key: InChIKey=OOPDFVLJBFXGIN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 183237   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183237 (US9150546, I-407 | US9688643, I-407 | US9718790, I...) Show SMILES CC(C)Oc1ccc(cc1Cl)\N=c1/[nH]c(=O)n(CCC(C)(C)C(=O)OCc2ccccc2)c(=O)n1Cc1ccc(Cl)cc1 Show InChI InChI=1S/C32H34Cl2N4O5/c1-21(2)43-27-15-14-25(18-26(27)34)35-29-36-30(40)37(31(41)38(29)19-22-10-12-24(33)13-11-22)17-16-32(3,4)28(39)42-20-23-8-6-5-7-9-23/h5-15,18,21H,16-17,19-20H2,1-4H3,(H,35,36,40)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	7.5	37
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9150546 (2015) BindingDB Entry DOI: 10.7270/Q2416VV1
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183237 (US9150546, I-407 | US9688643, I-407 | US9718790, I...) Show SMILES CC(C)Oc1ccc(cc1Cl)\N=c1/[nH]c(=O)n(CCC(C)(C)C(=O)OCc2ccccc2)c(=O)n1Cc1ccc(Cl)cc1 Show InChI InChI=1S/C32H34Cl2N4O5/c1-21(2)43-27-15-14-25(18-26(27)34)35-29-36-30(40)37(31(41)38(29)19-22-10-12-24(33)13-11-22)17-16-32(3,4)28(39)42-20-23-8-6-5-7-9-23/h5-15,18,21H,16-17,19-20H2,1-4H3,(H,35,36,40)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	7.5	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...				US Patent US9718790 (2017) BindingDB Entry DOI: 10.7270/Q22809KB
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183237 (US9150546, I-407 | US9688643, I-407 | US9718790, I...) Show SMILES CC(C)Oc1ccc(cc1Cl)\N=c1/[nH]c(=O)n(CCC(C)(C)C(=O)OCc2ccccc2)c(=O)n1Cc1ccc(Cl)cc1 Show InChI InChI=1S/C32H34Cl2N4O5/c1-21(2)43-27-15-14-25(18-26(27)34)35-29-36-30(40)37(31(41)38(29)19-22-10-12-24(33)13-11-22)17-16-32(3,4)28(39)42-20-23-8-6-5-7-9-23/h5-15,18,21H,16-17,19-20H2,1-4H3,(H,35,36,40)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9688643 (2017) BindingDB Entry DOI: 10.7270/Q2M32SZ2
					More data for this Ligand-Target Pair