null

SMILES: COC(=O)C(C)(C)Cn1c(=O)[nH]\c(=N/c2ccc(OC(C)C)c(Cl)c2)n(CC2CCCCCC2)c1=O

InChI Key: InChIKey=NEKLZKIZXQWIFI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 183375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183375 (US9150546, I-549 | US9688643, I-549 | US9718790, I...) Show SMILES COC(=O)C(C)(C)Cn1c(=O)[nH]\c(=N/c2ccc(OC(C)C)c(Cl)c2)n(CC2CCCCCC2)c1=O Show InChI InChI=1S/C26H37ClN4O5/c1-17(2)36-21-13-12-19(14-20(21)27)28-23-29-24(33)31(16-26(3,4)22(32)35-5)25(34)30(23)15-18-10-8-6-7-9-11-18/h12-14,17-18H,6-11,15-16H2,1-5H3,(H,28,29,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	7.5	37
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9150546 (2015) BindingDB Entry DOI: 10.7270/Q2416VV1
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183375 (US9150546, I-549 | US9688643, I-549 | US9718790, I...) Show SMILES COC(=O)C(C)(C)Cn1c(=O)[nH]\c(=N/c2ccc(OC(C)C)c(Cl)c2)n(CC2CCCCCC2)c1=O Show InChI InChI=1S/C26H37ClN4O5/c1-17(2)36-21-13-12-19(14-20(21)27)28-23-29-24(33)31(16-26(3,4)22(32)35-5)25(34)30(23)15-18-10-8-6-7-9-11-18/h12-14,17-18H,6-11,15-16H2,1-5H3,(H,28,29,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	7.5	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...				US Patent US9718790 (2017) BindingDB Entry DOI: 10.7270/Q22809KB
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183375 (US9150546, I-549 | US9688643, I-549 | US9718790, I...) Show SMILES COC(=O)C(C)(C)Cn1c(=O)[nH]\c(=N/c2ccc(OC(C)C)c(Cl)c2)n(CC2CCCCCC2)c1=O Show InChI InChI=1S/C26H37ClN4O5/c1-17(2)36-21-13-12-19(14-20(21)27)28-23-29-24(33)31(16-26(3,4)22(32)35-5)25(34)30(23)15-18-10-8-6-7-9-11-18/h12-14,17-18H,6-11,15-16H2,1-5H3,(H,28,29,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9688643 (2017) BindingDB Entry DOI: 10.7270/Q2M32SZ2
					More data for this Ligand-Target Pair