BDBM184139 US9150566, 177

SMILES: Cc1cccc(C(=O)N2CCOC[C@H]2Cc2cc(ccc2F)-c2ncon2)c1-n1nccn1

InChI Key: InChIKey=OQWDRLJUBNCFEY-GOSISDBHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 184139   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM184139 (US9150566, 177) Show SMILES Cc1cccc(C(=O)N2CCOC[C@H]2Cc2cc(ccc2F)-c2ncon2)c1-n1nccn1 Show InChI InChI=1S/C23H21FN6O3/c1-15-3-2-4-19(21(15)30-26-7-8-27-30)23(31)29-9-10-32-13-18(29)12-17-11-16(5-6-20(17)24)22-25-14-33-28-22/h2-8,11,14,18H,9-10,12-13H2,1H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	893	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9150566 (2015) BindingDB Entry DOI: 10.7270/Q2M32TJ3
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM184139 (US9150566, 177) Show SMILES Cc1cccc(C(=O)N2CCOC[C@H]2Cc2cc(ccc2F)-c2ncon2)c1-n1nccn1 Show InChI InChI=1S/C23H21FN6O3/c1-15-3-2-4-19(21(15)30-26-7-8-27-30)23(31)29-9-10-32-13-18(29)12-17-11-16(5-6-20(17)24)22-25-14-33-28-22/h2-8,11,14,18H,9-10,12-13H2,1H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9150566 (2015) BindingDB Entry DOI: 10.7270/Q2M32TJ3
					More data for this Ligand-Target Pair