BDBM185174 N-[2-[4-(adamantane-1-carbonyl)piperazin-1-yl]-2-oxo-ethyl]ethenesulfonamide (2e)

SMILES: C=CS(=O)(=O)NCC(=O)N1CCN(CC1)C(=O)C12CC3CC(CC(C3)C1)C2

InChI Key: InChIKey=LINUYDQSQBYGPV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 185174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-glutamine gamma-glutamyltransferase 2 (TG2) (Homo sapiens (Human))	BDBM185174 (N-[2-[4-(adamantane-1-carbonyl)piperazin-1-yl]-2-o...) Show SMILES C=CS(=O)(=O)NCC(=O)N1CCN(CC1)C(=O)C12CC3CC(CC(C3)C1)C2 |TLB:20:21:25:19.24.18,24:19:26:23.25.22,24:23:26:20.19.18,THB:20:19:25:26.21.22| Show InChI InChI=1S/C19H29N3O4S/c1-2-27(25,26)20-13-17(23)21-3-5-22(6-4-21)18(24)19-10-14-7-15(11-19)9-16(8-14)12-19/h2,14-16,20H,1,3-13H2	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	875	n/a	n/a	n/a	n/a	n/a	n/a
Aston University					Assay Description For measurement of TG2 activity, the incorporation of biotinylated cadaverineinto immobilized N,N-dimethylcasein was used as described previously (Wa...				Chem Biol 22: 1347-61 (2015) Article DOI: 10.1016/j.chembiol.2015.08.013 BindingDB Entry DOI: 10.7270/Q2222SJC
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