BDBM185826 US9163003, 17::USRE46942, Example 16
SMILES: COc1ccc2C(=O)C3(Cc2c1)CCN(CC3)[C@@H]1CCN(Cc2nc3CCOCc3c(=O)[nH]2)C1=O
InChI Key: InChIKey=FMURKSCWRQGCFO-OAQYLSRUSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human)) | BDBM185826 (US9163003, 17 | USRE46942, Example 16) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.72E+3 | n/a | n/a | n/a | n/a | n/a | 25 |
NOVARTIS AG US Patent | Assay Description The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ... | US Patent US9163003 (2015) BindingDB Entry DOI: 10.7270/Q2QN65J6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Poly [ADP-ribose] polymerase tankyrase-1 (Homo sapiens (Human)) | BDBM185826 (US9163003, 17 | USRE46942, Example 16) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ... | US Patent USRE46942 (2018) BindingDB Entry DOI: 10.7270/Q2VX0JVH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human)) | BDBM185826 (US9163003, 17 | USRE46942, Example 16) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <8.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ... | US Patent USRE46942 (2018) BindingDB Entry DOI: 10.7270/Q2VX0JVH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Poly [ADP-ribose] polymerase tankyrase-1 (Homo sapiens (Human)) | BDBM185826 (US9163003, 17 | USRE46942, Example 16) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.85E+3 | n/a | n/a | n/a | n/a | n/a | 25 |
NOVARTIS AG US Patent | Assay Description The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ... | US Patent US9163003 (2015) BindingDB Entry DOI: 10.7270/Q2QN65J6 | |||||||||||
More data for this Ligand-Target Pair |