null

SMILES: C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(O)=O)C(O)=O

InChI Key: InChIKey=LZHDSWPVMITKJX-NSHDSACASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185951   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185951 (US9163008, 40) Show SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C20H16FN3O5/c1-11(19(25)26)22-17-10-16(20(27)28)23-18(24-17)12-2-6-14(7-3-12)29-15-8-4-13(21)5-9-15/h2-11H,1H3,(H,25,26)(H,27,28)(H,22,23,24)/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.11E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185951 (US9163008, 40) Show SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C20H16FN3O5/c1-11(19(25)26)22-17-10-16(20(27)28)23-18(24-17)12-2-6-14(7-3-12)29-15-8-4-13(21)5-9-15/h2-11H,1H3,(H,25,26)(H,27,28)(H,22,23,24)/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair