BDBM186252 US9163015, 38

SMILES: FC(F)(F)c1cccc(c1)C(=O)c1ccc(Nc2n[nH]c3cccnc23)cc1Cl

InChI Key: InChIKey=VFWHRLINFIBILX-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 186252   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186252 (US9163015, 38) Show SMILES FC(F)(F)c1cccc(c1)C(=O)c1ccc(Nc2n[nH]c3cccnc23)cc1Cl Show InChI InChI=1S/C20H12ClF3N4O/c21-15-10-13(26-19-17-16(27-28-19)5-2-8-25-17)6-7-14(15)18(29)11-3-1-4-12(9-11)20(22,23)24/h1-10H,(H2,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	3.88E+3	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
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