BDBM186257 US9163015, 43

SMILES: Fc1c(Cl)cc(Nc2n[nH]c3cccnc23)cc1Cl

InChI Key: InChIKey=WGTVTOIDLDFGBS-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 186257   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM186257 (US9163015, 43) Show SMILES Fc1c(Cl)cc(Nc2n[nH]c3cccnc23)cc1Cl Show InChI InChI=1S/C12H7Cl2FN4/c13-7-4-6(5-8(14)10(7)15)17-12-11-9(18-19-12)2-1-3-16-11/h1-5H,(H2,17,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				US Patent US9163015 (2015) BindingDB Entry DOI: 10.7270/Q2JW8CNN
					More data for this Ligand-Target Pair