BDBM18836 4-(2-methylbutan-2-yl)phenyl prop-2-enoate::Substituted Acrylate, 6d

SMILES: CCC(C)(C)c1ccc(OC(=O)C=C)cc1

InChI Key: InChIKey=YJNVZFRESYAKPQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18836   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid Hormone Receptor (TR-beta) (Homo sapiens (Human))	BDBM18836 (4-(2-methylbutan-2-yl)phenyl prop-2-enoate | Subst...) Show SMILES CCC(C)(C)c1ccc(OC(=O)C=C)cc1 Show InChI InChI=1S/C14H18O2/c1-5-13(15)16-12-9-7-11(8-10-12)14(3,4)6-2/h5,7-10H,1,6H2,2-4H3	PDB MMDB B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Research Hospital					Assay Description IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...				J Med Chem 50: 5269-5280 (2007) Article DOI: 10.1021/jm070556y BindingDB Entry DOI: 10.7270/Q24B2ZK8
					More data for this Ligand-Target Pair
Thyroid Hormone Receptor (TR-alpha) (Homo sapiens (Human))	BDBM18836 (4-(2-methylbutan-2-yl)phenyl prop-2-enoate | Subst...) Show SMILES CCC(C)(C)c1ccc(OC(=O)C=C)cc1 Show InChI InChI=1S/C14H18O2/c1-5-13(15)16-12-9-7-11(8-10-12)14(3,4)6-2/h5,7-10H,1,6H2,2-4H3	PDB MMDB B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.96E+4	n/a	n/a	n/a	n/a	7.2	22
St. Jude Research Hospital					Assay Description IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...				J Med Chem 50: 5269-5280 (2007) Article DOI: 10.1021/jm070556y BindingDB Entry DOI: 10.7270/Q24B2ZK8
					More data for this Ligand-Target Pair