BDBM188629 US9169246, 167

SMILES: Nc1cnccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1

InChI Key: InChIKey=ZKHFDMGDNSSRGL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 188629   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM188629 (US9169246, 167) Show SMILES Nc1cnccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1 Show InChI InChI=1S/C17H12F3N5O/c18-17(19,20)8-25-14-5-9(10-3-4-22-7-13(10)21)1-2-11(14)15-12(16(25)26)6-23-24-15/h1-7H,8,21H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.64	n/a	n/a	n/a	n/a	n/a	n/a
SANOFI US Patent					Assay Description The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...				US Patent US9169246 (2015) BindingDB Entry DOI: 10.7270/Q2B856XZ
					More data for this Ligand-Target Pair