BDBM188674 US9169246, 214

SMILES: FC(F)(F)Cn1c2cc(ccc2c2[nH]ncc2c1=O)-c1ccccc1C(=O)NCCc1ccncc1

InChI Key: InChIKey=NCCFERDPDWYDAC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 188674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM188674 (US9169246, 214) Show SMILES FC(F)(F)Cn1c2cc(ccc2c2[nH]ncc2c1=O)-c1ccccc1C(=O)NCCc1ccncc1 Show InChI InChI=1S/C26H20F3N5O2/c27-26(28,29)15-34-22-13-17(5-6-20(22)23-21(25(34)36)14-32-33-23)18-3-1-2-4-19(18)24(35)31-12-9-16-7-10-30-11-8-16/h1-8,10-11,13-14H,9,12,15H2,(H,31,35)(H,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12.9	n/a	n/a	n/a	n/a	n/a	n/a
SANOFI US Patent					Assay Description The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...				US Patent US9169246 (2015) BindingDB Entry DOI: 10.7270/Q2B856XZ
					More data for this Ligand-Target Pair