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BDBM188702 US9169246, 244

SMILES: FC(F)(F)Cn1c2cc(ccc2c2[nH]ncc2c1=O)-c1cccnc1N1CCCNCC1

InChI Key: InChIKey=ZBFZSKYNUAQWCA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 188702   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (Human))
BDBM188702
PNG
(US9169246, 244)
Show SMILES FC(F)(F)Cn1c2cc(ccc2c2[nH]ncc2c1=O)-c1cccnc1N1CCCNCC1
Show InChI InChI=1S/C22H21F3N6O/c23-22(24,25)13-31-18-11-14(4-5-16(18)19-17(21(31)32)12-28-29-19)15-3-1-7-27-20(15)30-9-2-6-26-8-10-30/h1,3-5,7,11-12,26H,2,6,8-10,13H2,(H,28,29)
PDB
MMDB

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Similars

US Patent
n/an/a 6.08n/an/an/an/an/an/a



SANOFI

US Patent


Assay Description
The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...


US Patent US9169246 (2015)


BindingDB Entry DOI: 10.7270/Q2B856XZ
More data for this
Ligand-Target Pair