BDBM188712 US9169246, 254

SMILES: FC(F)(F)Cn1c2cc(ccc2c2[nH]ncc2c1=O)-c1cccnc1N1CCC1

InChI Key: InChIKey=SWEFIISHSBBBSS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 188712   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM188712 (US9169246, 254) Show SMILES FC(F)(F)Cn1c2cc(ccc2c2[nH]ncc2c1=O)-c1cccnc1N1CCC1 Show InChI InChI=1S/C20H16F3N5O/c21-20(22,23)11-28-16-9-12(13-3-1-6-24-18(13)27-7-2-8-27)4-5-14(16)17-15(19(28)29)10-25-26-17/h1,3-6,9-10H,2,7-8,11H2,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
SANOFI US Patent					Assay Description The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...				US Patent US9169246 (2015) BindingDB Entry DOI: 10.7270/Q2B856XZ
					More data for this Ligand-Target Pair