BDBM190962 US10077266, Example 75::US9181249, 75::US9708313, 75

SMILES: CC(C)Nc1nc2CN(C)CCc2nc1N1CCC(CC1)C(F)c1ccc(F)cc1F

InChI Key: InChIKey=LNHWNOWSQBYDGD-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 190962   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 6 (Homo sapiens (Human))	BDBM190962 (US10077266, Example 75 | US9181249, 75 | US9708313...) Show SMILES CC(C)Nc1nc2CN(C)CCc2nc1N1CCC(CC1)C(F)c1ccc(F)cc1F Show InChI InChI=1S/C23H30F3N5/c1-14(2)27-22-23(29-19-8-9-30(3)13-20(19)28-22)31-10-6-15(7-11-31)21(26)17-5-4-16(24)12-18(17)25/h4-5,12,14-15,21H,6-11,13H2,1-3H3,(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0303	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...				US Patent US9181249 (2015) BindingDB Entry DOI: 10.7270/Q2HM577D
					More data for this Ligand-Target Pair
G-protein coupled receptor 6 (Homo sapiens (Human))	BDBM190962 (US10077266, Example 75 | US9181249, 75 | US9708313...) Show SMILES CC(C)Nc1nc2CN(C)CCc2nc1N1CCC(CC1)C(F)c1ccc(F)cc1F Show InChI InChI=1S/C23H30F3N5/c1-14(2)27-22-23(29-19-8-9-30(3)13-20(19)28-22)31-10-6-15(7-11-31)21(26)17-5-4-16(24)12-18(17)25/h4-5,12,14-15,21H,6-11,13H2,1-3H3,(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...				US Patent US9708313 (2017) BindingDB Entry DOI: 10.7270/Q2ZP4858
					More data for this Ligand-Target Pair
G-protein coupled receptor 6 (Homo sapiens (Human))	BDBM190962 (US10077266, Example 75 | US9181249, 75 | US9708313...) Show SMILES CC(C)Nc1nc2CN(C)CCc2nc1N1CCC(CC1)C(F)c1ccc(F)cc1F Show InChI InChI=1S/C23H30F3N5/c1-14(2)27-22-23(29-19-8-9-30(3)13-20(19)28-22)31-10-6-15(7-11-31)21(26)17-5-4-16(24)12-18(17)25/h4-5,12,14-15,21H,6-11,13H2,1-3H3,(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...				US Patent US10077266 (2018) BindingDB Entry DOI: 10.7270/Q2T155PB
					More data for this Ligand-Target Pair