BDBM192128 US9187437, 13

SMILES: Fc1cc(ccc1C(F)(F)F)-c1noc(CCC2(CCCCC2)c2ccccc2)n1

InChI Key: InChIKey=XJOXSXUGPLCLSO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192128   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM192128 (US9187437, 13) Show SMILES Fc1cc(ccc1C(F)(F)F)-c1noc(CCC2(CCCCC2)c2ccccc2)n1 Show InChI InChI=1S/C23H22F4N2O/c24-19-15-16(9-10-18(19)23(25,26)27)21-28-20(30-29-21)11-14-22(12-5-2-6-13-22)17-7-3-1-4-8-17/h1,3-4,7-10,15H,2,5-6,11-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	7.5	25
BRISTOL-MYERS SQUIBB COMPANY US Patent					Assay Description Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1x108 cells/pellet) were suspended in buffer containing 20 mM HEPES, pH ...				US Patent US9187437 (2015) BindingDB Entry DOI: 10.7270/Q2JH3K0X
					More data for this Ligand-Target Pair