BDBM192129 US9187437, 20

SMILES: Fc1ccccc1COc1ccc(cc1)-c1noc(CCC2(CCCCC2)c2ccccc2)n1

InChI Key: InChIKey=NOUUBEAAHXABFN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192129   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM192129 (US9187437, 20) Show SMILES Fc1ccccc1COc1ccc(cc1)-c1noc(CCC2(CCCCC2)c2ccccc2)n1 Show InChI InChI=1S/C29H29FN2O2/c30-26-12-6-5-9-23(26)21-33-25-15-13-22(14-16-25)28-31-27(34-32-28)17-20-29(18-7-2-8-19-29)24-10-3-1-4-11-24/h1,3-6,9-16H,2,7-8,17-21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	410	n/a	n/a	n/a	n/a	7.5	25
BRISTOL-MYERS SQUIBB COMPANY US Patent					Assay Description Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1x108 cells/pellet) were suspended in buffer containing 20 mM HEPES, pH ...				US Patent US9187437 (2015) BindingDB Entry DOI: 10.7270/Q2JH3K0X
					More data for this Ligand-Target Pair