BDBM192132 US9187437, 17::US9187437, 28

SMILES: Fc1ccc(-c2noc(CCC3(CCCCC3)c3ccccc3)n2)c(F)c1

InChI Key: InChIKey=IEHOOLMQRMNLOQ-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 192132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM192132 (US9187437, 17 | US9187437, 28) Show SMILES Fc1ccc(-c2noc(CCC3(CCCCC3)c3ccccc3)n2)c(F)c1 Show InChI InChI=1S/C22H22F2N2O/c23-17-9-10-18(19(24)15-17)21-25-20(27-26-21)11-14-22(12-5-2-6-13-22)16-7-3-1-4-8-16/h1,3-4,7-10,15H,2,5-6,11-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	7.5	25
BRISTOL-MYERS SQUIBB COMPANY US Patent					Assay Description Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1x108 cells/pellet) were suspended in buffer containing 20 mM HEPES, pH ...				US Patent US9187437 (2015) BindingDB Entry DOI: 10.7270/Q2JH3K0X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM192132 (US9187437, 17 | US9187437, 28) Show SMILES Fc1ccc(-c2noc(CCC3(CCCCC3)c3ccccc3)n2)c(F)c1 Show InChI InChI=1S/C22H22F2N2O/c23-17-9-10-18(19(24)15-17)21-25-20(27-26-21)11-14-22(12-5-2-6-13-22)16-7-3-1-4-8-16/h1,3-4,7-10,15H,2,5-6,11-14H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	60
BRISTOL-MYERS SQUIBB COMPANY US Patent					Assay Description Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-G...				US Patent US9187437 (2015) BindingDB Entry DOI: 10.7270/Q2JH3K0X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM192132 (US9187437, 17 | US9187437, 28) Show SMILES Fc1ccc(-c2noc(CCC3(CCCCC3)c3ccccc3)n2)c(F)c1 Show InChI InChI=1S/C22H22F2N2O/c23-17-9-10-18(19(24)15-17)21-25-20(27-26-21)11-14-22(12-5-2-6-13-22)16-7-3-1-4-8-16/h1,3-4,7-10,15H,2,5-6,11-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	740	n/a	n/a	n/a	60
BRISTOL-MYERS SQUIBB COMPANY US Patent					Assay Description Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-G...				US Patent US9187437 (2015) BindingDB Entry DOI: 10.7270/Q2JH3K0X
					More data for this Ligand-Target Pair