BDBM192599 US9187486, 72

SMILES: C[C@@H]1C[C@H](N)CN(C1)c1ccncc1Nc1ncc2ccc(nn12)-c1cc(ccc1F)C(=O)NC1CC1

InChI Key: InChIKey=AENSKLYNJAPICQ-AEFFLSMTSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 192599   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM192599 (US9187486, 72) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1Nc1ncc2ccc(nn12)-c1cc(ccc1F)C(=O)NC1CC1 |r| Show InChI InChI=1S/C27H29FN8O/c1-16-10-18(29)15-35(14-16)25-8-9-30-13-24(25)33-27-31-12-20-5-7-23(34-36(20)27)21-11-17(2-6-22(21)28)26(37)32-19-3-4-19/h2,5-9,11-13,16,18-19H,3-4,10,14-15,29H2,1H3,(H,31,33)(H,32,37)/t16-,18+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9187486 (2015) BindingDB Entry DOI: 10.7270/Q24748NM
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM192599 (US9187486, 72) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1Nc1ncc2ccc(nn12)-c1cc(ccc1F)C(=O)NC1CC1 |r| Show InChI InChI=1S/C27H29FN8O/c1-16-10-18(29)15-35(14-16)25-8-9-30-13-24(25)33-27-31-12-20-5-7-23(34-36(20)27)21-11-17(2-6-22(21)28)26(37)32-19-3-4-19/h2,5-9,11-13,16,18-19H,3-4,10,14-15,29H2,1H3,(H,31,33)(H,32,37)/t16-,18+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9187486 (2015) BindingDB Entry DOI: 10.7270/Q24748NM
					More data for this Ligand-Target Pair