BDBM192650 N’-(phenylmethylene)benzohydrazide (1a)

SMILES: O=C(N\N=C\c1ccccc1)c1ccccc1

InChI Key: InChIKey=RISHSDLMXPLIHT-RVDMUPIBSA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 192650   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin L (Capra hircus (Goat))	BDBM192650 (N’-(phenylmethylene)benzohydrazide (1a)) Show SMILES O=C(N\N=C\c1ccccc1)c1ccccc1 Show InChI InChI=1S/C14H12N2O/c17-14(13-9-5-2-6-10-13)16-15-11-12-7-3-1-4-8-12/h1-11H,(H,16,17)/b15-11+	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	13	-11.2	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin B (Capra hircus (Goat))	BDBM192650 (N’-(phenylmethylene)benzohydrazide (1a)) Show SMILES O=C(N\N=C\c1ccccc1)c1ccccc1 Show InChI InChI=1S/C14H12N2O/c17-14(13-9-5-2-6-10-13)16-15-11-12-7-3-1-4-8-12/h1-11H,(H,16,17)/b15-11+	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	290	-9.27	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin H (Capra hircus (Goat))	BDBM192650 (N’-(phenylmethylene)benzohydrazide (1a)) Show SMILES O=C(N\N=C\c1ccccc1)c1ccccc1 Show InChI InChI=1S/C14H12N2O/c17-14(13-9-5-2-6-10-13)16-15-11-12-7-3-1-4-8-12/h1-11H,(H,16,17)/b15-11+	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.14E+3	-8.04	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
3C-like proteinase (CVB3 3Cpro) (Coxsackievirus B3 (strain Nancy))	BDBM192650 (N’-(phenylmethylene)benzohydrazide (1a)) Show SMILES O=C(N\N=C\c1ccccc1)c1ccccc1 Show InChI InChI=1S/C14H12N2O/c17-14(13-9-5-2-6-10-13)16-15-11-12-7-3-1-4-8-12/h1-11H,(H,16,17)/b15-11+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gwangju Institute of Science and Technology (GIST) Curated by ChEMBL					Assay Description Inhibition of recombinant Coxsackievirus B3 3C protease expressed in Escherichia coli BL21 (DE3) preincubated for 5 mins followed by addition of NMA-...				Eur J Med Chem 120: 202-16 (2016) Article DOI: 10.1016/j.ejmech.2016.03.085 BindingDB Entry DOI: 10.7270/Q25B05HD
					More data for this Ligand-Target Pair