BDBM192906 US9193689, IQ-157

SMILES: Cc1cccc2c1cc([nH]c2=O)-c1cnc(nc1)N1CCN(CC1)C(=O)C1CC1

InChI Key: InChIKey=QUSZOYLWBHWZLQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192906   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tankyrase-1 (TNKS1) (Homo sapiens (Human))	BDBM192906 (US9193689, IQ-157) Show SMILES Cc1cccc2c1cc([nH]c2=O)-c1cnc(nc1)N1CCN(CC1)C(=O)C1CC1 Show InChI InChI=1S/C22H23N5O2/c1-14-3-2-4-17-18(14)11-19(25-20(17)28)16-12-23-22(24-13-16)27-9-7-26(8-10-27)21(29)15-5-6-15/h2-4,11-13,15H,5-10H2,1H3,(H,25,28)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (THE) US Patent					Assay Description Tankyrase activity was assayed using a 96-well format HT Universal Chemiluminescent PARP Assay Kit (Trevigen, Inc, cat. no. 4676-096-K) according to ...				US Patent US9193689 (2015) BindingDB Entry DOI: 10.7270/Q29S1PTR
					More data for this Ligand-Target Pair