Found 5 hits for monomerid = 192987 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
(Homo sapiens (Human)) | BDBM192987
![PNG](/data/jpeg/tenK19/BindingDB_192987.png) (US10526329, Compound 167 | US11072611, Compound 16...)Show SMILES CCc1nc2ccc(cn2c1N(C)c1nc(cs1)-c1ccc(F)cc1C#N)N1CCN(CC(=O)N2CCC2)CC1 Show InChI InChI=1S/C29H31FN8OS/c1-3-24-28(34(2)29-33-25(19-40-29)23-7-5-21(30)15-20(23)16-31)38-17-22(6-8-26(38)32-24)36-13-11-35(12-14-36)18-27(39)37-9-4-10-37/h5-8,15,17,19H,3-4,9-14,18H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | 8.5 | 25 |
GALAPAGOS NV
US Patent
| Assay Description Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate. 5 μL of a di... |
US Patent US9670204 (2017)
BindingDB Entry DOI: 10.7270/Q2W66HZS |
More data for this Ligand-Target Pair | |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
(Homo sapiens (Human)) | BDBM192987
![PNG](/data/jpeg/tenK19/BindingDB_192987.png) (US10526329, Compound 167 | US11072611, Compound 16...)Show SMILES CCc1nc2ccc(cn2c1N(C)c1nc(cs1)-c1ccc(F)cc1C#N)N1CCN(CC(=O)N2CCC2)CC1 Show InChI InChI=1S/C29H31FN8OS/c1-3-24-28(34(2)29-33-25(19-40-29)23-7-5-21(30)15-20(23)16-31)38-17-22(6-8-26(38)32-24)36-13-11-35(12-14-36)18-27(39)37-9-4-10-37/h5-8,15,17,19H,3-4,9-14,18H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV
US Patent
| Assay Description Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil... |
US Patent US10526329 (2020)
BindingDB Entry DOI: 10.7270/Q2Z60RGR |
More data for this Ligand-Target Pair | |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
(Homo sapiens (Human)) | BDBM192987
![PNG](/data/jpeg/tenK19/BindingDB_192987.png) (US10526329, Compound 167 | US11072611, Compound 16...)Show SMILES CCc1nc2ccc(cn2c1N(C)c1nc(cs1)-c1ccc(F)cc1C#N)N1CCN(CC(=O)N2CCC2)CC1 Show InChI InChI=1S/C29H31FN8OS/c1-3-24-28(34(2)29-33-25(19-40-29)23-7-5-21(30)15-20(23)16-31)38-17-22(6-8-26(38)32-24)36-13-11-35(12-14-36)18-27(39)37-9-4-10-37/h5-8,15,17,19H,3-4,9-14,18H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
(Homo sapiens (Human)) | BDBM192987
![PNG](/data/jpeg/tenK19/BindingDB_192987.png) (US10526329, Compound 167 | US11072611, Compound 16...)Show SMILES CCc1nc2ccc(cn2c1N(C)c1nc(cs1)-c1ccc(F)cc1C#N)N1CCN(CC(=O)N2CCC2)CC1 Show InChI InChI=1S/C29H31FN8OS/c1-3-24-28(34(2)29-33-25(19-40-29)23-7-5-21(30)15-20(23)16-31)38-17-22(6-8-26(38)32-24)36-13-11-35(12-14-36)18-27(39)37-9-4-10-37/h5-8,15,17,19H,3-4,9-14,18H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
(Homo sapiens (Human)) | BDBM192987
![PNG](/data/jpeg/tenK19/BindingDB_192987.png) (US10526329, Compound 167 | US11072611, Compound 16...)Show SMILES CCc1nc2ccc(cn2c1N(C)c1nc(cs1)-c1ccc(F)cc1C#N)N1CCN(CC(=O)N2CCC2)CC1 Show InChI InChI=1S/C29H31FN8OS/c1-3-24-28(34(2)29-33-25(19-40-29)23-7-5-21(30)15-20(23)16-31)38-17-22(6-8-26(38)32-24)36-13-11-35(12-14-36)18-27(39)37-9-4-10-37/h5-8,15,17,19H,3-4,9-14,18H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV
US Patent
| |
US Patent US10526329 (2020)
BindingDB Entry DOI: 10.7270/Q2Z60RGR |
More data for this Ligand-Target Pair | |