BDBM193121 US9193736, 37

SMILES: Oc1nc(no1)-c1ccc(cn1)-c1c(CCc2ccc3ccccc3n2)nc2c(ccnn12)N1CCOCC1

InChI Key: InChIKey=WKUZOJBCXZABGX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 193121   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 10A (PDE10A2) (Homo sapiens (Human))	BDBM193121 (US9193736, 37) Show SMILES Oc1nc(no1)-c1ccc(cn1)-c1c(CCc2ccc3ccccc3n2)nc2c(ccnn12)N1CCOCC1 Show InChI InChI=1S/C28H24N8O3/c37-28-33-26(34-39-28)23-9-6-19(17-29-23)25-22(10-8-20-7-5-18-3-1-2-4-21(18)31-20)32-27-24(11-12-30-36(25)27)35-13-15-38-16-14-35/h1-7,9,11-12,17H,8,10,13-16H2,(H,33,34,37)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica, NV US Patent					Assay Description Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...				US Patent US9193736 (2015) BindingDB Entry DOI: 10.7270/Q2XK8DCS
					More data for this Ligand-Target Pair
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat))	BDBM193121 (US9193736, 37) Show SMILES Oc1nc(no1)-c1ccc(cn1)-c1c(CCc2ccc3ccccc3n2)nc2c(ccnn12)N1CCOCC1 Show InChI InChI=1S/C28H24N8O3/c37-28-33-26(34-39-28)23-9-6-19(17-29-23)25-22(10-8-20-7-5-18-3-1-2-4-21(18)31-20)32-27-24(11-12-30-36(25)27)35-13-15-38-16-14-35/h1-7,9,11-12,17H,8,10,13-16H2,(H,33,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.8	n/a
Janssen Pharmaceutica, NV US Patent					Assay Description Rat recombinant PDE10a (rPDE10a) was expressed in Sf9 cells using a recombinant rPDE10a baculovirus construct. Cells were harvested after 48 h of inf...				US Patent US9193736 (2015) BindingDB Entry DOI: 10.7270/Q2XK8DCS
					More data for this Ligand-Target Pair