BDBM19339 N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}-2-(1H-indol-3-yl)ethyl]piperidine-4-carboxamide::Trisubstituted 1,2,4-Triazole, 47

SMILES: CCc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)cc1

InChI Key: InChIKey=PROMAYDRALXCHH-JGCGQSQUSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM19339 (N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-5-(2-phenylet...) Show SMILES CCc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)cc1 |r| Show InChI InChI=1S/C35H40N6O/c1-2-25-12-14-27(15-13-25)24-41-33(17-16-26-8-4-3-5-9-26)39-40-34(41)32(38-35(42)28-18-20-36-21-19-28)22-29-23-37-31-11-7-6-10-30(29)31/h3-15,23,28,32,36-37H,2,16-22,24H2,1H3,(H,38,42)/t32-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	7.70	n/a	n/a	n/a	n/a
CNRS					Assay Description Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...				J Med Chem 50: 5790-5806 (2007) Article DOI: 10.1021/jm0704550 BindingDB Entry DOI: 10.7270/Q2HD7SZ4
					More data for this Ligand-Target Pair