null
SMILES: Clc1cc(Cl)c(cc1Cl)S(=O)(=O)Nc1ccccc1SSc1ccccc1NS(=O)(=O)c1cc(Cl)c(Cl)cc1Cl
InChI Key: InChIKey=GPAWQZJLNFOMKW-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-glucuronidase (Bos taurus (Bovine)) | BDBM193670 (N,N'-(disulfanediylbis(2,1-phenylene))bis(2,4,...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA | Assay Description β-glucuronidase activity was determined by measuring absorbance at 405 nm of p-nitrophenol formed substrate by spectrophotometric method. 250 µL... | Bioorg Chem 68: 15-22 (2016) Article DOI: 10.1016/j.bioorg.2016.07.002 BindingDB Entry DOI: 10.7270/Q2542MCP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-glucuronidase (Homo sapiens (Human)) | BDBM193670 (N,N'-(disulfanediylbis(2,1-phenylene))bis(2,4,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of KwaZulu-Natal Curated by ChEMBL | Assay Description Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-d-glucuronide as substrate after 30 mins | Eur J Med Chem 187: (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-glucuronidase (Homo sapiens (Human)) | BDBM193670 (N,N'-(disulfanediylbis(2,1-phenylene))bis(2,4,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of KwaZulu-Natal Curated by ChEMBL | Assay Description Inhibition of beta-glucuronidase (unknown origin) | Eur J Med Chem 187: (2020) | |||||||||||
More data for this Ligand-Target Pair |