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BDBM193677 N'-[(Z)-(2,4-dichlorophenyl)methylidene]-2-hydroxybenzohydrazide (6)

SMILES: Oc1ccccc1C(=O)N\N=C/c1ccc(Cl)cc1Cl

InChI Key: InChIKey=VAZJVBLBYMOKTK-IUXPMGMMSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 193677   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholinesterases


(Homo sapiens (Human))
BDBM193677
PNG
(N'-[(Z)-(2,4-dichlorophenyl)methylidene]-2-hyd...)
Show SMILES Oc1ccccc1C(=O)N\N=C/c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C14H10Cl2N2O2/c15-10-6-5-9(12(16)7-10)8-17-18-14(20)11-3-1-2-4-13(11)19/h1-8,19H,(H,18,20)/b17-8-
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.32E+4n/an/an/an/a7.7n/a



Hazara University



Assay Description
Total volume of the reaction mixture was 100 無 containing 60 無, Na2HPO4 buffer, 50 mM and pH 7.7. Ten 無 test compound 0.5 mM well-1 was added foll...


Bioorg Chem 68: 30-40 (2016)


Article DOI: 10.1016/j.bioorg.2016.07.005
BindingDB Entry DOI: 10.7270/Q21C1VPD
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Tetronarce californica (Pacific electric ray) (Tor...)
BDBM193677
PNG
(N'-[(Z)-(2,4-dichlorophenyl)methylidene]-2-hyd...)
Show SMILES Oc1ccccc1C(=O)N\N=C/c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C14H10Cl2N2O2/c15-10-6-5-9(12(16)7-10)8-17-18-14(20)11-3-1-2-4-13(11)19/h1-8,19H,(H,18,20)/b17-8-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.81E+4n/an/an/an/a7.7n/a



Hazara University



Assay Description
Total volume of the reaction mixture was 100 無. It contained 60 無 Na2HPO4 buffer with concentration of 50 mM and pH 7.7. 10 無 test compound (0.5 m...


Bioorg Chem 68: 30-40 (2016)


Article DOI: 10.1016/j.bioorg.2016.07.005
BindingDB Entry DOI: 10.7270/Q21C1VPD
More data for this
Ligand-Target Pair