null
SMILES: Cc1cc(ccc1C(=O)NC1(C)CC1)-c1cnc2c(NCCC(F)(F)F)nc(cn12)C#CCO
InChI Key: InChIKey=BPBRGYAWEYXCDB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM194259 (US9199999, 73) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 120 | n/a | n/a | n/a | n/a | 7.7 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description N-terminally GST-tagged human full length recombinant Mps-1 kinase (purchased from Invitrogen, Karslruhe, Germany, cat. no PV4071 ) was used. As subs... | US Patent US9199999 (2015) BindingDB Entry DOI: 10.7270/Q2348J68 | |||||||||||
More data for this Ligand-Target Pair |