null

SMILES: CCn1cc(C(=O)C2CC2)c2cc(Nc3ncc(F)c(n3)-n3cc(CN4C[C@H](O)CO4)c(C)n3)ccc12

InChI Key: InChIKey=KCQSZKBRMVTRRJ-IBGZPJMESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 196791   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM196791 (US9212178, 20 | US9212178, 21) Show SMILES CCn1cc(C(=O)C2CC2)c2cc(Nc3ncc(F)c(n3)-n3cc(CN4C[C@H](O)CO4)c(C)n3)ccc12 |r| Show InChI InChI=1S/C26H28FN7O3/c1-3-32-13-21(24(36)16-4-5-16)20-8-18(6-7-23(20)32)29-26-28-9-22(27)25(30-26)34-11-17(15(2)31-34)10-33-12-19(35)14-37-33/h6-9,11,13,16,19,35H,3-5,10,12,14H2,1-2H3,(H,28,29,30)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	25
Genosco; Oscotec, Inc. US Patent					Assay Description Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...				US Patent US9212178 (2015) BindingDB Entry DOI: 10.7270/Q2X9294C
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM196791 (US9212178, 20 | US9212178, 21) Show SMILES CCn1cc(C(=O)C2CC2)c2cc(Nc3ncc(F)c(n3)-n3cc(CN4C[C@H](O)CO4)c(C)n3)ccc12 |r| Show InChI InChI=1S/C26H28FN7O3/c1-3-32-13-21(24(36)16-4-5-16)20-8-18(6-7-23(20)32)29-26-28-9-22(27)25(30-26)34-11-17(15(2)31-34)10-33-12-19(35)14-37-33/h6-9,11,13,16,19,35H,3-5,10,12,14H2,1-2H3,(H,28,29,30)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	66.2	n/a	n/a	n/a	n/a	n/a	25
Genosco; Oscotec, Inc. US Patent					Assay Description Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...				US Patent US9212178 (2015) BindingDB Entry DOI: 10.7270/Q2X9294C
					More data for this Ligand-Target Pair