BDBM197349 US9216962, CFH381-C

SMILES: ONC(=O)CCCCCNC(=O)c1nc(sc1C1CC1)-c1nccs1

InChI Key: InChIKey=ABSSTWUONYNFRT-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 197349   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM197349 (US9216962, CFH381-C) Show SMILES ONC(=O)CCCCCNC(=O)c1nc(sc1C1CC1)-c1nccs1 Show InChI InChI=1S/C16H20N4O3S2/c21-11(20-23)4-2-1-3-7-17-14(22)12-13(10-5-6-10)25-16(19-12)15-18-8-9-24-15/h8-10,23H,1-7H2,(H,17,22)(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Puyi Chemical Co., Ltd. US Patent					Assay Description Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...				US Patent US9216962 (2015) BindingDB Entry DOI: 10.7270/Q2QJ7G3F
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM197349 (US9216962, CFH381-C) Show SMILES ONC(=O)CCCCCNC(=O)c1nc(sc1C1CC1)-c1nccs1 Show InChI InChI=1S/C16H20N4O3S2/c21-11(20-23)4-2-1-3-7-17-14(22)12-13(10-5-6-10)25-16(19-12)15-18-8-9-24-15/h8-10,23H,1-7H2,(H,17,22)(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Puyi Chemical Co., Ltd. US Patent					Assay Description Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...				US Patent US9216962 (2015) BindingDB Entry DOI: 10.7270/Q2QJ7G3F
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM197349 (US9216962, CFH381-C) Show SMILES ONC(=O)CCCCCNC(=O)c1nc(sc1C1CC1)-c1nccs1 Show InChI InChI=1S/C16H20N4O3S2/c21-11(20-23)4-2-1-3-7-17-14(22)12-13(10-5-6-10)25-16(19-12)15-18-8-9-24-15/h8-10,23H,1-7H2,(H,17,22)(H,20,21)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Puyi Chemical Co., Ltd. US Patent					Assay Description Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...				US Patent US9216962 (2015) BindingDB Entry DOI: 10.7270/Q2QJ7G3F
					More data for this Ligand-Target Pair