BDBM197362 US9216962, CFH449-H
SMILES: ONC(=O)CCCCCCNC(=O)c1nc(sc1C1CC1)-c1nc2CCCCc2s1
InChI Key: InChIKey=HEXCVAOOHDWROK-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM197362 (US9216962, CFH449-H) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Puyi Chemical Co., Ltd. US Patent | Assay Description Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate... | US Patent US9216962 (2015) BindingDB Entry DOI: 10.7270/Q2QJ7G3F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cereblon/Histone deacetylase 6 (Homo sapiens (Human)) | BDBM197362 (US9216962, CFH449-H) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Puyi Chemical Co., Ltd. US Patent | Assay Description Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate... | US Patent US9216962 (2015) BindingDB Entry DOI: 10.7270/Q2QJ7G3F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 3 (Homo sapiens (Human)) | BDBM197362 (US9216962, CFH449-H) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Puyi Chemical Co., Ltd. US Patent | Assay Description Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate... | US Patent US9216962 (2015) BindingDB Entry DOI: 10.7270/Q2QJ7G3F | |||||||||||
More data for this Ligand-Target Pair |