BDBM197761 US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-ethyl]-5-fluoro-quinoline::US9801878, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-ethyl]-5-fluoro-quinoline

SMILES: Cc1ncc(C)n2nc(CCc3ccc4c(F)cccc4n3)nc12

InChI Key: InChIKey=YCQZMYCKKNSEKA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197761   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM197761 (US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...) Show SMILES Cc1ncc(C)n2nc(CCc3ccc4c(F)cccc4n3)nc12 Show InChI InChI=1S/C18H16FN5/c1-11-10-20-12(2)18-22-17(23-24(11)18)9-7-13-6-8-14-15(19)4-3-5-16(14)21-13/h3-6,8,10H,7,9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9801878 (2017) BindingDB Entry DOI: 10.7270/Q26Q20CD
					More data for this Ligand-Target Pair
PED10A (Homo sapiens (Human))	BDBM197761 (US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...) Show SMILES Cc1ncc(C)n2nc(CCc3ccc4c(F)cccc4n3)nc12 Show InChI InChI=1S/C18H16FN5/c1-11-10-20-12(2)18-22-17(23-24(11)18)9-7-13-6-8-14-15(19)4-3-5-16(14)21-13/h3-6,8,10H,7,9H2,1-2H3	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9216986 (2015) BindingDB Entry DOI: 10.7270/Q2Z31XG5
					More data for this Ligand-Target Pair