Found 6 hits for monomerid = 198030 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM198030
(US9221795, 26)Show SMILES CC[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2c(F)ccc(Cl)c2c(=O)n1-c1cccnc1 |r| Show InChI InChI=1S/C21H17ClFN9O/c1-2-14(28-18-11(8-24)17(25)30-21(26)31-18)19-29-16-13(23)6-5-12(22)15(16)20(33)32(19)10-4-3-7-27-9-10/h3-7,9,14H,2H2,1H3,(H5,25,26,28,30,31)/t14-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Gilead Sciences, Inc.
US Patent
| Assay Description
Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu... |
US Patent US9221795 (2015)
BindingDB Entry DOI: 10.7270/Q29C6W8T |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM198030
(US9221795, 26)Show SMILES CC[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2c(F)ccc(Cl)c2c(=O)n1-c1cccnc1 |r| Show InChI InChI=1S/C21H17ClFN9O/c1-2-14(28-18-11(8-24)17(25)30-21(26)31-18)19-29-16-13(23)6-5-12(22)15(16)20(33)32(19)10-4-3-7-27-9-10/h3-7,9,14H,2H2,1H3,(H5,25,26,28,30,31)/t14-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM198030
(US9221795, 26)Show SMILES CC[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2c(F)ccc(Cl)c2c(=O)n1-c1cccnc1 |r| Show InChI InChI=1S/C21H17ClFN9O/c1-2-14(28-18-11(8-24)17(25)30-21(26)31-18)19-29-16-13(23)6-5-12(22)15(16)20(33)32(19)10-4-3-7-27-9-10/h3-7,9,14H,2H2,1H3,(H5,25,26,28,30,31)/t14-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human)) | BDBM198030
(US9221795, 26)Show SMILES CC[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2c(F)ccc(Cl)c2c(=O)n1-c1cccnc1 |r| Show InChI InChI=1S/C21H17ClFN9O/c1-2-14(28-18-11(8-24)17(25)30-21(26)31-18)19-29-16-13(23)6-5-12(22)15(16)20(33)32(19)10-4-3-7-27-9-10/h3-7,9,14H,2H2,1H3,(H5,25,26,28,30,31)/t14-/m0/s1 | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM198030
(US9221795, 26)Show SMILES CC[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2c(F)ccc(Cl)c2c(=O)n1-c1cccnc1 |r| Show InChI InChI=1S/C21H17ClFN9O/c1-2-14(28-18-11(8-24)17(25)30-21(26)31-18)19-29-16-13(23)6-5-12(22)15(16)20(33)32(19)10-4-3-7-27-9-10/h3-7,9,14H,2H2,1H3,(H5,25,26,28,30,31)/t14-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human)) | BDBM198030
(US9221795, 26)Show SMILES CC[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2c(F)ccc(Cl)c2c(=O)n1-c1cccnc1 |r| Show InChI InChI=1S/C21H17ClFN9O/c1-2-14(28-18-11(8-24)17(25)30-21(26)31-18)19-29-16-13(23)6-5-12(22)15(16)20(33)32(19)10-4-3-7-27-9-10/h3-7,9,14H,2H2,1H3,(H5,25,26,28,30,31)/t14-/m0/s1 | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
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