BDBM198658 US9221791, 4::US9556143, 4
SMILES: CCOC(=O)\C=C\c1ccc(nc1)C(F)(F)C(O)(Cn1cnnn1)c1ccc(F)cc1F
InChI Key: InChIKey=OSXQTSNGAHYVDC-XBXARRHUSA-N
Data: 6 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 2C9 (Homo sapiens (Human)) | BDBM198658 (US9221791, 4 | US9556143, 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Viamet Pharmaceuticals, Inc. US Patent | Assay Description Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:M... | US Patent US9221791 (2015) BindingDB Entry DOI: 10.7270/Q24M93B6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM198658 (US9221791, 4 | US9556143, 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.66E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Viamet Pharmaceuticals, Inc. US Patent | Assay Description Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:M... | US Patent US9221791 (2015) BindingDB Entry DOI: 10.7270/Q24M93B6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM198658 (US9221791, 4 | US9556143, 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Viamet Pharmaceuticals, Inc. US Patent | US Patent US9556143 (2017) BindingDB Entry DOI: 10.7270/Q2NG4SMF | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C9 (Homo sapiens (Human)) | BDBM198658 (US9221791, 4 | US9556143, 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Viamet Pharmaceuticals, Inc. US Patent | Assay Description Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 μM by serial dilution with DMS... | US Patent US9556143 (2017) BindingDB Entry DOI: 10.7270/Q2NG4SMF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM198658 (US9221791, 4 | US9556143, 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.66E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Viamet Pharmaceuticals, Inc. US Patent | US Patent US9556143 (2017) BindingDB Entry DOI: 10.7270/Q2NG4SMF | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM198658 (US9221791, 4 | US9556143, 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Viamet Pharmaceuticals, Inc. US Patent | Assay Description Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial dilution with DMSO:M... | US Patent US9221791 (2015) BindingDB Entry DOI: 10.7270/Q24M93B6 | |||||||||||
More data for this Ligand-Target Pair |