BDBM19915 3-(2-fluoro-4-hydroxyphenyl)-5,7-dihydroxy-3,4-dihydroquinazolin-4-one::3-arylquinazolinone, 1ag

SMILES: Oc1ccc(c(F)c1)-n1cnc2cc(O)cc(O)c2c1=O

InChI Key: InChIKey=DLPVDFZWWHWMEZ-UHFFFAOYSA-N

Data: 2 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19915   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor beta (Homo sapiens (Human))	BDBM19915 (3-(2-fluoro-4-hydroxyphenyl)-5,7-dihydroxy-3,4-dih...) Show SMILES Oc1ccc(c(F)c1)-n1cnc2cc(O)cc(O)c2c1=O Show InChI InChI=1S/C14H9FN2O4/c15-9-3-7(18)1-2-11(9)17-6-16-10-4-8(19)5-12(20)13(10)14(17)21/h1-6,18-20H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	256	n/a	190	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19915 (3-(2-fluoro-4-hydroxyphenyl)-5,7-dihydroxy-3,4-dih...) Show SMILES Oc1ccc(c(F)c1)-n1cnc2cc(O)cc(O)c2c1=O Show InChI InChI=1S/C14H9FN2O4/c15-9-3-7(18)1-2-11(9)17-6-16-10-4-8(19)5-12(20)13(10)14(17)21/h1-6,18-20H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.49E+3	n/a	1.14E+3	n/a	n/a	8.0	22
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair