BDBM199329 US9676818, 41

SMILES: CCCCCCCCCCCCCc1cn(CCSC[C@H](NC(C)=O)C(=O)N[C@@H](CO)C(=O)OC)nn1

InChI Key: InChIKey=BKVVOLPGQOSQKG-ZEQRLZLVSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 199329   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 2 (TLR2) (Homo sapiens (Human))	BDBM199329 (US9676818, 41) Show SMILES CCCCCCCCCCCCCc1cn(CCSC[C@H](NC(C)=O)C(=O)N[C@@H](CO)C(=O)OC)nn1 |r| Show InChI InChI=1S/C26H47N5O5S/c1-4-5-6-7-8-9-10-11-12-13-14-15-22-18-31(30-29-22)16-17-37-20-24(27-21(2)33)25(34)28-23(19-32)26(35)36-3/h18,23-24,32H,4-17,19-20H2,1-3H3,(H,27,33)(H,28,34)/t23-,24-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.60E+5	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...				US Patent US9676818 (2017) BindingDB Entry DOI: 10.7270/Q2TB1539
					More data for this Ligand-Target Pair