BDBM199436 US9676818, 82

SMILES: CCCCCCCCCCC[C@H](CC(=O)OCCSC[C@H](NC(C)=O)C(=O)N[C@@H](CO)C(=O)OC)OC(C)=O

InChI Key: InChIKey=RUMWPMCWJTYPCO-SGNDLWITSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 199436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 2 (TLR2) (Homo sapiens (Human))	BDBM199436 (US9676818, 82) Show SMILES CCCCCCCCCCC[C@H](CC(=O)OCCSC[C@H](NC(C)=O)C(=O)N[C@@H](CO)C(=O)OC)OC(C)=O |r| Show InChI InChI=1S/C27H48N2O9S/c1-5-6-7-8-9-10-11-12-13-14-22(38-21(3)32)17-25(33)37-15-16-39-19-24(28-20(2)31)26(34)29-23(18-30)27(35)36-4/h22-24,30H,5-19H2,1-4H3,(H,28,31)(H,29,34)/t22-,23+,24+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	182	n/a	n/a	n/a	n/a
University of Kansas US Patent					Assay Description The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...				US Patent US9676818 (2017) BindingDB Entry DOI: 10.7270/Q2TB1539
					More data for this Ligand-Target Pair