BDBM200981 US9233946, 80

SMILES: OC(=O)c1cccc(NS(=O)(=O)c2cccc(c2)-c2ccccc2)c1

InChI Key: InChIKey=VMDAPLBIOHQKQX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200981   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) (Homo sapiens (Human))	BDBM200981 (US9233946, 80) Show SMILES OC(=O)c1cccc(NS(=O)(=O)c2cccc(c2)-c2ccccc2)c1 Show InChI InChI=1S/C19H15NO4S/c21-19(22)16-9-4-10-17(12-16)20-25(23,24)18-11-5-8-15(13-18)14-6-2-1-3-7-14/h1-13,20H,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description Method B: The kinase activity of the bi-functional enzyme is readily quantified based on the production of ADP and F-2,6-P2 from ATP and F6P. The ADP...				US Patent US9233946 (2016) BindingDB Entry DOI: 10.7270/Q2V123KB
					More data for this Ligand-Target Pair