BDBM202293 US9540357, example 3::US9540357, example 4

SMILES: OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1ccccc1

InChI Key: InChIKey=JICJGHOUTJHCSR-MALRFLDTSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 202293   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202293 (US9540357, example 3 | US9540357, example 4) Show SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C23H25NO4/c25-21(18-6-2-1-3-7-18)14-12-20-13-15-22(26)24(20)16-4-5-17-8-10-19(11-9-17)23(27)28/h1-3,6-12,14,20-21,25H,4-5,13,15-16H2,(H,27,28)/b14-12+/t20-,21?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.97E+3	-7.23	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202293 (US9540357, example 3 | US9540357, example 4) Show SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C23H25NO4/c25-21(18-6-2-1-3-7-18)14-12-20-13-15-22(26)24(20)16-4-5-17-8-10-19(11-9-17)23(27)28/h1-3,6-12,14,20-21,25H,4-5,13,15-16H2,(H,27,28)/b14-12+/t20-,21?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	>-6.82	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202293 (US9540357, example 3 | US9540357, example 4) Show SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C23H25NO4/c25-21(18-6-2-1-3-7-18)14-12-20-13-15-22(26)24(20)16-4-5-17-8-10-19(11-9-17)23(27)28/h1-3,6-12,14,20-21,25H,4-5,13,15-16H2,(H,27,28)/b14-12+/t20-,21?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	>-6.82	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202293 (US9540357, example 3 | US9540357, example 4) Show SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C23H25NO4/c25-21(18-6-2-1-3-7-18)14-12-20-13-15-22(26)24(20)16-4-5-17-8-10-19(11-9-17)23(27)28/h1-3,6-12,14,20-21,25H,4-5,13,15-16H2,(H,27,28)/b14-12+/t20-,21?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	>-6.82	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair