BDBM202985 US9242970, 133

SMILES: COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1cccc(c1)-c1csc(C)n1

InChI Key: InChIKey=LRUWAFBAMKJJRR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 202985   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 1 (Homo sapiens (Human))	BDBM202985 (US9242970, 133) Show SMILES COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1cccc(c1)-c1csc(C)n1 Show InChI InChI=1S/C24H26N2O3S/c1-15-11-20(23-21(28-3)9-6-10-22(23)29-4)26(24(15)27)13-17-7-5-8-18(12-17)19-14-30-16(2)25-19/h5-10,12,14-15,20H,11,13H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description In Vitro Assay: Intracellular Calcium Measurements:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 re...				US Patent US9242970 (2016) BindingDB Entry DOI: 10.7270/Q2R49PK4
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM202985 (US9242970, 133) Show SMILES COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1cccc(c1)-c1csc(C)n1 Show InChI InChI=1S/C24H26N2O3S/c1-15-11-20(23-21(28-3)9-6-10-22(23)29-4)26(24(15)27)13-17-7-5-8-18(12-17)19-14-30-16(2)25-19/h5-10,12,14-15,20H,11,13H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description In Vitro Assay: Intracellular Calcium Measurements:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 re...				US Patent US9242970 (2016) BindingDB Entry DOI: 10.7270/Q2R49PK4
					More data for this Ligand-Target Pair