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SMILES: CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2C(C)Cn3c(cc4c(F)cccc34)-c2n1)-c1ccc(F)cc1

InChI Key: InChIKey=SNAPSRUTHMAAQQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 204727   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM204727 (US9243002, 62) Show SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2C(C)Cn3c(cc4c(F)cccc34)-c2n1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H28F2N4O4S/c1-18-17-40-27-7-5-6-25(36)22(27)15-29(40)32-21(18)12-13-26(38-32)23-14-24-30(16-28(23)39(3)45(4,42)43)44-33(31(24)34(41)37-2)19-8-10-20(35)11-9-19/h5-16,18H,17H2,1-4H3,(H,37,41)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.55	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...				US Patent US9243002 (2016) BindingDB Entry DOI: 10.7270/Q2P55MBC
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM204727 (US9243002, 62) Show SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2C(C)Cn3c(cc4c(F)cccc34)-c2n1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H28F2N4O4S/c1-18-17-40-27-7-5-6-25(36)22(27)15-29(40)32-21(18)12-13-26(38-32)23-14-24-30(16-28(23)39(3)45(4,42)43)44-33(31(24)34(41)37-2)19-8-10-20(35)11-9-19/h5-16,18H,17H2,1-4H3,(H,37,41)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.69	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...				US Patent US9243002 (2016) BindingDB Entry DOI: 10.7270/Q2P55MBC
					More data for this Ligand-Target Pair