BDBM205006 US9249096, 17

SMILES: CN1C(C(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O)C(C)(C)C

InChI Key: InChIKey=JLHGGGSVJIGYGK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 205006   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM205006 (US9249096, 17) Show SMILES CN1C(C(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O)C(C)(C)C |t:18| Show InChI InChI=1S/C19H24Cl2N2O3/c1-19(2,3)16-14(15(24)18(26)23(16)4)17(25)22-9-5-6-11-7-8-12(20)13(21)10-11/h7-8,10,16,24H,5-6,9H2,1-4H3,(H,22,25)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	430	n/a	n/a	n/a	n/a	8.0	37
Bristol-Myers Squibb Company US Patent					Assay Description The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 uL of assay buffer (50 mM HEPES pH 8.0, 50 mM N...				US Patent US9249096 (2016) BindingDB Entry DOI: 10.7270/Q2RX99X0
					More data for this Ligand-Target Pair