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SMILES: CCCCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O

InChI Key: InChIKey=HUCLTXHWXFAGPM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 205033   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelial lipase


(Homo sapiens (Human))		BDBM205033
PNG
(US9249096, 46)
Show SMILES CCCCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O |t:21|
Show InChI InChI=1S/C18H22Cl2N2O3/c1-2-3-9-22-11-13(16(23)18(22)25)17(24)21-8-4-5-12-6-7-14(19)15(20)10-12/h6-7,10,23H,2-5,8-9,11H2,1H3,(H,21,24)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.25n/an/an/an/a8.037



Bristol-Myers Squibb Company

US Patent


Assay Description
The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 uL of assay buffer (50 mM HEPES pH 8.0, 50 mM N...

US Patent US9249096 (2016)


BindingDB Entry DOI: 10.7270/Q2RX99X0
More data for this
Ligand-Target Pair