BDBM205034 US9249096, 47

SMILES: OC1=C(CN(Cc2cccc(Cl)c2)C1=O)C(=O)NCCCc1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=PKXYIAQHQHIJLQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 205034   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM205034 (US9249096, 47) Show SMILES OC1=C(CN(Cc2cccc(Cl)c2)C1=O)C(=O)NCCCc1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C21H19Cl3N2O3/c22-15-5-1-3-14(9-15)11-26-12-16(19(27)21(26)29)20(28)25-8-2-4-13-6-7-17(23)18(24)10-13/h1,3,5-7,9-10,27H,2,4,8,11-12H2,(H,25,28)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	8.0	37
Bristol-Myers Squibb Company US Patent					Assay Description The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 uL of assay buffer (50 mM HEPES pH 8.0, 50 mM N...				US Patent US9249096 (2016) BindingDB Entry DOI: 10.7270/Q2RX99X0
					More data for this Ligand-Target Pair