BDBM205047 US9249096, 64

SMILES: OC1=C(CN(CCc2ccc(F)cc2)C1=O)C(=O)NCCCc1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=UJWCYFGZFDBFPV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 205047   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM205047 (US9249096, 64) Show SMILES OC1=C(CN(CCc2ccc(F)cc2)C1=O)C(=O)NCCCc1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C22H21Cl2FN2O3/c23-18-8-5-15(12-19(18)24)2-1-10-26-21(29)17-13-27(22(30)20(17)28)11-9-14-3-6-16(25)7-4-14/h3-8,12,28H,1-2,9-11,13H2,(H,26,29)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.61	n/a	n/a	n/a	n/a	8.0	37
Bristol-Myers Squibb Company US Patent					Assay Description The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 uL of assay buffer (50 mM HEPES pH 8.0, 50 mM N...				US Patent US9249096 (2016) BindingDB Entry DOI: 10.7270/Q2RX99X0
					More data for this Ligand-Target Pair