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SMILES: FC(F)(F)c1cccc(n1)N1CC[C@H](C1)NC(=O)Nc1ccccc1Br

InChI Key: InChIKey=GWMMUQRQTPSSAP-LLVKDONJSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20505   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20505
PNG
(1-(2-bromophenyl)-3-[(3R)-1-[6-(trifluoromethyl)py...)
Show SMILES FC(F)(F)c1cccc(n1)N1CC[C@H](C1)NC(=O)Nc1ccccc1Br |r|
Show InChI InChI=1S/C17H16BrF3N4O/c18-12-4-1-2-5-13(12)23-16(26)22-11-8-9-25(10-11)15-7-3-6-14(24-15)17(19,20)21/h1-7,11H,8-10H2,(H2,22,23,26)/t11-/m1/s1
PDB
MMDB

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PC cid
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Article
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n/an/an/an/a 63n/an/a7.225



GSK



Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...

Bioorg Med Chem Lett 16: 3287-91 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.030
BindingDB Entry DOI: 10.7270/Q2125QX9
More data for this
Ligand-Target Pair