BDBM205148 US9249096, 230

SMILES: CC(C)C(CCc1ccc(Cl)c(Cl)c1)NC(=O)C1=C(O)C(=O)N(C)C1

InChI Key: InChIKey=GHDFDEIYNVCALK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 205148   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM205148 (US9249096, 230) Show SMILES CC(C)C(CCc1ccc(Cl)c(Cl)c1)NC(=O)C1=C(O)C(=O)N(C)C1 |c:18| Show InChI InChI=1S/C18H22Cl2N2O3/c1-10(2)15(7-5-11-4-6-13(19)14(20)8-11)21-17(24)12-9-22(3)18(25)16(12)23/h4,6,8,10,15,23H,5,7,9H2,1-3H3,(H,21,24)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.64E+3	n/a	n/a	n/a	n/a	8.0	37
Bristol-Myers Squibb Company US Patent					Assay Description The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 uL of assay buffer (50 mM HEPES pH 8.0, 50 mM N...				US Patent US9249096 (2016) BindingDB Entry DOI: 10.7270/Q2RX99X0
					More data for this Ligand-Target Pair