BDBM205167 US9249096, 294

SMILES: CN1CC(C(=O)NCCCc2ccccc2C(F)(F)F)=C(O)C1=O

InChI Key: InChIKey=LQFVWYSAGPICNX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 205167   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM205167 (US9249096, 294) Show SMILES CN1CC(C(=O)NCCCc2ccccc2C(F)(F)F)=C(O)C1=O |t:20| Show InChI InChI=1S/C16H17F3N2O3/c1-21-9-11(13(22)15(21)24)14(23)20-8-4-6-10-5-2-3-7-12(10)16(17,18)19/h2-3,5,7,22H,4,6,8-9H2,1H3,(H,20,23)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	436	n/a	n/a	n/a	n/a	8.0	37
Bristol-Myers Squibb Company US Patent					Assay Description The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 uL of assay buffer (50 mM HEPES pH 8.0, 50 mM N...				US Patent US9249096 (2016) BindingDB Entry DOI: 10.7270/Q2RX99X0
					More data for this Ligand-Target Pair