null

SMILES: CC(=O)Nc1nc2c(Oc3cc(ncn3)N3CCC(CC3)C(F)(F)F)cccc2s1

InChI Key: InChIKey=DIEWRDPAJIXNPT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20563   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM20563 (N-[4-({6-[4-(trifluoromethyl)piperidin-1-yl]pyrimi...) Show SMILES CC(=O)Nc1nc2c(Oc3cc(ncn3)N3CCC(CC3)C(F)(F)F)cccc2s1 Show InChI InChI=1S/C19H18F3N5O2S/c1-11(28)25-18-26-17-13(3-2-4-14(17)30-18)29-16-9-15(23-10-24-16)27-7-5-12(6-8-27)19(20,21)22/h2-4,9-10,12H,5-8H2,1H3,(H,25,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...				J Med Chem 50: 3528-39 (2007) Article DOI: 10.1021/jm070191h BindingDB Entry DOI: 10.7270/Q2MW2FF4
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM20563 (N-[4-({6-[4-(trifluoromethyl)piperidin-1-yl]pyrimi...) Show SMILES CC(=O)Nc1nc2c(Oc3cc(ncn3)N3CCC(CC3)C(F)(F)F)cccc2s1 Show InChI InChI=1S/C19H18F3N5O2S/c1-11(28)25-18-26-17-13(3-2-4-14(17)30-18)29-16-9-15(23-10-24-16)27-7-5-12(6-8-27)19(20,21)22/h2-4,9-10,12H,5-8H2,1H3,(H,25,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	7.4	22
Amgen					Assay Description TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...				J Med Chem 50: 3528-39 (2007) Article DOI: 10.1021/jm070191h BindingDB Entry DOI: 10.7270/Q2MW2FF4
					More data for this Ligand-Target Pair